Cannabidiol (CBD) Isomerization to Psychoactive Cannabinoids

[thcman]

Could someone please send some simple steps i have tried to extract with distilled water and syringe but when adding alcohol to the oil it turned purple?

 

[Uncle Lee]

Turning purple means that your product contains a high percentage of CBD and that your ethanol solution is mixed with alkaline substances

 

[Uncle Lee]

Why don't you try the citric acid isomerization method I posted in this forum, this reagent is easily available worldwide.
If you need a slightly larger scale or industrial scale production you can contact me and I can help you design it for a fee, but it requires some special reagents.
Any other questions you can leave a message and I will help you for free

 

[Montecristo]

For NPS, can I use naptha without issue?

 

[Uncle Lee]

Naphtha is not exactly the same from region to region, you need to test, this solvent evaporates without any residue and dissolves THC easily, then it is OK

 

[Montecristo]

Okay thank you, its the nap i use for DMT extractions and from that I know that it dries without residue but not sure about THC solubility. I could distill the DCM out of some paint stripper though, so I might do that first and then compare with with nap. Or I could try with nap first to see if it dissolves the THC, and have DCM on hand if it doesn't. Id rather use nap if possible due to it being cheap and accessible, I can update when i try this and let everyone know how it turns out comparatively .
When you speak of recycling the NPS, you mean via distillation ? if so, how would you recommend getting the product out of the boiling flask?
thanks!! I'm very excited to try this!!

 

[Uncle Lee]

I prefer to use low boiling point solvents, if you do not want to recycle just water bath the solution directly in the outdoor evaporation, you need to recover the solvent then just distillation, if you are a home laboratory, you can pour the solution out into a flat bottom container when a small amount of solvent remains, water bath and evaporate the solvent, if you make large quantities, you can private message me

 

[thcman]

Is isopropyl alcohol viable, what are the best solvents other than ethanol

 

[thcman]

Should I leave Stiring when adding
Bicarb and water and how long should I leave to neutralise

 

[thcman]

 

[Uncle Lee]

Isopropyl alcohol should be fine, but you want to make sure no isopropyl alcohol is left in your product. I rarely try to use ethanol as a solvent, I'm not familiar with that approach

You need to stir, the reaction will be gaseous in the presence of acid, the neutralization is very fast and you don't need to wait long

 

[thcman]

Is it safe to boil off the acid, it looks good on the video are their any bi products for
Rom this and does it effect the isomerisation

 

[Uncle Lee]

Without trying to boil out the acid, you can absolutely use a base and then extract with NP, wash, dry, and evaporate the solvent to obtain THC, which is very simple to do, just try

 

[thcman]

Is hexane viable what is the safest option i like ethanol ol as seems safe and has no toxicity so you know any route with just ethanol

 

[thcman]

Hexane would dilute with ethanol and thc to be extra sure its all boiled off, do you know of any websites with videos this is quite a common thing there alot of patents and recipes o google but I can't find d any with ethanol or hexane, do you know how to purify thc and re isomer cbd I have had some insights but reagents are toxic

 

[thcman]

The video i saw isn't on here anymore is it safe to boil off acetic acid, should be getting np hexane soon I want some more research on toxicity before I do that what temperature should It evaporate off at

 

[Uncle Lee]

It is theoretically safe for smoking, in fact I don't know what by-products are produced by boiling the solvent, perhaps acetate or acetyl products
If you have enough time you can let the solution evaporate until only the paste THC and a small amount of liquid remains, then extract with hexane, wash the organic phase with sodium bicarbonate solution, wash the organic phase with distilled water, dry the organic phase with anhydrous sodium sulphate and evaporate the solvent to obtain THC

 

[thcman]

I do understand that way I don't have non polar ,hexane yet I am trying to make e liquid what should the product smell and taste like and are their ways to test for negative byproducts, is acetate dangerous valine or smoking its not vitamine e acetate what would make this product dangerous

 

[WillD]

For the perfect can be used HCl aq. soln.

 

[JoeShit]

I'm using bulk CBD and I don't think it's been winterized. When I ad baking soda to neutralize the acid it looks like all the fats and lipids crash out creating a very light and solid layer on the bottom, leaving alot of blackish liquid on top. I had desolved it in isopropyl alcahol from the beginning, so now I have the black liquid in a large plate to let the alcohol evaporate.