1-Phenyl-2-nitropropen (P2NP) Video Synthese aus Benzaldehyd und Nitroethan. Henry-Reaktion.

[HIGGS BOSSON]

Die Probleme mit Nitroethan in Europa begannen 2007, und nach und nach haben alle Länder Beschränkungen für dieses wertvolle Reagenz erlassen. Nun gibt es zwei Möglichkeiten: die Suche nach Lieferanten in Ländern mit schwacher Gesetzgebung und entwickelter chemischer Industrie, z. B. Bangladesch, oder die eigenständige Synthese, für die wir eine Methode vorgeschlagen haben.

 

[Alojz]

Wodurch kann man Nitroethan ersetzen oder selbst synthetisieren?

 

[Kvadprime]

You can find methods of syntes nitroethane in another thread

 

[Kvadprime]

I have aniline as a base - what yeilds can it give?

 

[G.Patton]

Try and figure out. Share us your research data. In theory, it's quite weak base and it would be not enough to eliminate -OH group.

 

[Kvadprime]

ok, I'll definitely write how everything went... I'm still waiting for my new labware to arrive

Thx

 

[rampage]

has anyone done the microwave version of this synthesis, curious as to the outcome?

 

[William D.]

This is an effective method. I irradiate at maximum power in short time intervals so that the mixture does not have time to boil.

 

[rampage]

that is the key, stopping the irradiation just prior or as soon as you see 1 tiny bubble rise up, did this method with very good success, simple but very effective. would be very interested if there's other synths that can be done using the microwave??