Video Syntéza 1-fenyl-2-nitropropenu (P2NP) z benzaldehydu a nitroetanu. Henryho reakce.

[HIGGS BOSSON]

Problémy s nitroethanem v Evropě začaly již v roce 2007, poté postupně všechny země zavedly omezení pro toto cenné činidlo. A nyní existují dvě možnosti: hledat dodavatele v zemích, kde je slabá legislativa s rozvinutým chemickým průmyslem, například v Bangladéši, nebo syntetizovat samostatně, metodiku k tomu jsme navrhli my.

 

[Alojz]

Čím lze nahradit nebo syntetizovat nitroethan?

 

[Kvadprime]

You can find methods of syntes nitroethane in another thread

 

[Kvadprime]

I have aniline as a base - what yeilds can it give?

 

[G.Patton]

Try and figure out. Share us your research data. In theory, it's quite weak base and it would be not enough to eliminate -OH group.

 

[Kvadprime]

ok, I'll definitely write how everything went... I'm still waiting for my new labware to arrive

Thx

 

[rampage]

has anyone done the microwave version of this synthesis, curious as to the outcome?

 

[William D.]

This is an effective method. I irradiate at maximum power in short time intervals so that the mixture does not have time to boil.

 

[rampage]

that is the key, stopping the irradiation just prior or as soon as you see 1 tiny bubble rise up, did this method with very good success, simple but very effective. would be very interested if there's other synths that can be done using the microwave??