Ephedrine extraction from plants
- Thread starter G.Patton
- Start date
Hello, I've come across information online that suggests that L-ephedrine and D-pseudoephedrine are the primary alkaloids found in ephedra, along with some other trace alkaloids. I think I’ve figured how to extract hydrochloride ephedrine and hydrochloride pseudoephedrine from ephedra and separating the two.
Could you please advise if I were to proceed with further meth synthesis, using methods like iodine/red phosphorus, should I use hydrochloride L-ephedrine, hydrochloride D-pseudoephedrine, or a mixture of both? Does the L/D have an impact on meth synthesis? Thank you.
I've encountered difficulty in distinguishing these concepts: ephedrine and pseudoephedrine, chiral L/D, optical rotation l/d, and I'm not sure how much they affect meth synthesis.
Could you please advise if I were to proceed with further meth synthesis, using methods like iodine/red phosphorus, should I use hydrochloride L-ephedrine, hydrochloride D-pseudoephedrine, or a mixture of both? Does the L/D have an impact on meth synthesis? Thank you.
I've encountered difficulty in distinguishing these concepts: ephedrine and pseudoephedrine, chiral L/D, optical rotation l/d, and I'm not sure how much they affect meth synthesis.
I used 15 grams of powder, each gram needs 1.656 ml, so 15 grams is 24.84 ml, but pouring ethanol and naphtha into the powder turned into mud. Excuse me, Great God, how can I filter it? There is no liquid at all, it's all mud.
There is a simplified method, which has been tested. Where does the powder obtained after heating with ethanol for 10 minutes in the first step go? Is it reserved for the second part? But in the second part, there is ethanol to soak for 3 days and naphtha to soak for 2 days, and then the two filtered liquids are fused. After fusion, a black substance with a lot of oil is obtained. I don't see powdery white.
- By G.Patton
I don't understand about what are you talking about. Can you write more clearly your request please?
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- By xiaofen
It was extracted step by step, but the final product was not white powder. I used a simplified version, and every step was done according to the above. After soaking in the solvent, the two solvents were combined, and after drying, a black one was obtained, no. It is a dark green liquid.
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- By G.Patton
In theory, your ephedrine is there. You just need to extract it. There are also other substances. You need to completely evaporate liquid and crystallize ephedrine. Probably, flash chromatography is necessary here.
can I use this method?
1000 grams (1 kg) of ephedra powder
5000 ml of water
3000 ml of gasoline
100 grams of table salt
20 grams of caustic soda
100 ml of concentrated sulfuric acid
1000 ml of xylene
method:
Soaking the powder in a mixture of water, gasoline, salt and soda for 24 hours
Strain the solution and transfer to the tank
Add sulfuric acid, salt and xylene
Heating at a temperature below 50 degrees Celsius for 2-3 hours
Separation and drying of sediment containing ephedrine
1000 grams (1 kg) of ephedra powder
5000 ml of water
3000 ml of gasoline
100 grams of table salt
20 grams of caustic soda
100 ml of concentrated sulfuric acid
1000 ml of xylene
method:
Soaking the powder in a mixture of water, gasoline, salt and soda for 24 hours
Strain the solution and transfer to the tank
Add sulfuric acid, salt and xylene
Heating at a temperature below 50 degrees Celsius for 2-3 hours
Separation and drying of sediment containing ephedrine
- By K.1
Have you ever tried this method? What was the yield like?
- By bigbadbear
I learned this method from one of my friends from Afghanistan. He said that they extract ephedrine with this method, but I haven't tried it yet because I'm looking for sulfuric acid.
CN103833559A - Extraction process of ephedrine - Google Patents
The invention relates to an extraction process of ephedrine, and belongs to the technical field of extraction of effective components in traditional Chinese medicines. The process provided by the invention comprises the following steps: pretreatment of ephedra; alkalization; extraction with...
patents.google.com
In coming months I will attempt an extraction and post results.