Simpel methylonsyntese (bk-MDMA)

[karamelosanto]

Hej, tak fordi du delte denne syntese, jeg synes, den er meget klar.
Jeg er fra Sydamerika, og her er det lidt svært at finde DCM. Jeg kan dog prøve at finde det på en eller anden måde. Måske købe det fra Kina.
Jeg vil gerne spørge. Kan du sætte alle regenter på en liste med mængder for at gøre det lidt lettere at forstå, hvad jeg skal købe. Hvis det er muligt med en anslået pris.
Tak!!!

 

[Professor11]

Pode me mandar uma mensagem? Sou da América do Sul também, estou iniciando na produção de Metilona.

 

[Marvin "Popcorn" Sutton]

Tabellen viser, at densiteten af 40 % methylamin er 0,89 g/cm3, og at der derfor opnås 7,18 g ren methylamingas i 20 ml.
Lad os sammenligne molekylvægten af methylamin og dets hydrochlorid:
M (CH3NH2)HCl = 67,518 g/mol
M CH3NH2 = 31,057 g/mol.
Forhold = 2,174
Hvis du bruger proportionerne fra syntesen, skal du bruge 15,6 g methylaminhydrochlorid til at erstatte 20 ml 40 % methylaminopløsning.
Methylaminhydrochlorid skal opløses på forhånd i forholdet 1 g til 2,5 ml vand (15,6 g og 39 ml).
Forbered en opløsning af natriumhydroxid (NaOH) på 18 g og 54 ml vand, lad den afkøle og hæld den i en kolbe med 2-brom-3,4-methylendioxypropiophenon-opløsning. Derefter tilsættes methylaminhydrochloridopløsning. Fortsæt derefter i henhold til instruktionerne.

 

[arundo]

Hello, I'm doing the math, and I see that the molar ratio of NaOH isn't equivalent with methylamine HCl. It doubles. It's for some reason?

 

[antrax]

Jeg vil prøve den kemiske syntese af bk-MDMA Jeg har allerede købt alle de nødvendige kemikalier, jeg vil starte direkte fra forstadiet 2-Bromo-3',4'-(methylendioxy)propiophenon (CAS-nummer: 52190-28-0), da jeg allerede har købt det fra en kinesisk kemikalieleverandør, og jeg betalte 280 dollars for 1 kg med forsendelse inkluderet, fra 25 kg betaler jeg 200 dollars for hvert kg.
kg med forsendelse inkluderet.

Jeg købte methylamin 40% vandig opløsning fra en polsk leverandør, selvom det ikke var en let opgave at finde det, og de andre kemiske produkter er let tilgængelige på det nationale marked, bortset fra 36% saltsyre, jeg fandt kun 35-38% saltsyre af analytisk kvalitet, som jeg købte, magnesiumsulfat vidste jeg ikke, hvilken jeg skulle købe, så jeg købte den vandfri.

Ácido clorhídrico 35-38% AGR Reag.Ph.Eur.

HCl

www.letslab.com

Magnesio Sulfato anhidro GLR

MgSO4

www.letslab.com

Jeg vil følge den følgende kemiske syntese af bk-MDMA, da den virker lettere end den, du delte, men jeg kan tage fejl, jeg vil gerne have dig til at give mig din mening.

http://bbzzzsvqcrqtki6umym6itiixfhni37ybtt7mkbjyxn2pgllzxf2qgyd.onion/threads/bk-mdma-synthesis-easy-and-fast-method.6423/

Tak skal du have!!!

 

[Eddybeaumont]

hello mate, can you give me an address to buy cas 52190-28-0 please?

 

[Osmosis Vanderwaal]

Someone asked me the other day about using sesamol to get MD-P1P, and it looked possible. Any opinion on that?

 

[William D.]

Doubtful route. If someone says how to do it simple, we will be glad.

 

[Wan Jack]

In a reaction kettle equipped with a condensing reflux, stirring, dropping and heating device, 111.3 g of catechol, 500 ml of dichloroethane and 166 g of ZnCl2 were added, stirred, cooled to 0-5°C, and 140 g of propionyl chloride was slowly added dropwise for about 2 hours, then the temperature was raised to 20°C and the reaction was continued for 15 hours. After the reaction was completed, water was added for dilution, and the organic phase was separated. The organic phase was sequentially acid-washed and washed with water, dried with sodium sulfate, desolventized, and the residue was recrystallized from ethanol to obtain 144 g of solid 3,4-dihydroxypropiophenone with a melting point of 145-146°C, a content of 98%, and a yield of 85%.

 

[William D.]

Yes, this method is more understandable. But I heard that you can use iodine as a Lewis acid catalyst. For more moderate conditions. I did not have time to check it, but I think that there is need study. Because the chinese intermediate of this substance have is of very poor quality, I think they have problems with the synthesis.

 

[Wan Jack]

Please refer to the next step( Patent: US1964973 , 1932)

 

[Wan Jack]

Sesamol Obtain MD-P1P No relevant information found

 

[Wan Jack]

Preparation of 3,4-methylenedioxypropiophenone
Methanesulfonic acid (MSA, 288 g) and propionic anhydride (156 g) were charged into a 1-liter reaction flask. The mixture was cooled to 0°C and 122 g of 3,4-methylenedioxybenzene (MDB) was added under stirring. The reaction mass was maintained at 0°C to 5°C for 4 hours under stirring. After the completion of the reaction, the reaction mass was diluted with water and the 3,4-methylenedioxypropiophenone product and unreacted MDB were extracted using toluene. The toluene layer was distilled to recover 13 g of unreacted MDB and obtain 142 g of 3',4'-methylenedioxypropiophenone (GC purity > 98%, yield 131% w/w based on consumed MDB). The water layer was distilled to recover 273 g of MSA (purity > 98%), which could be reused in subsequent batches.