Syntéza amfetaminu z P2NP pomocí Al/Hg (video)

[Marvin "Popcorn" Sutton]

Podle mých zkušeností je hliníková fólie nejlepší formou hliníku pro amalgám. Hlavní podmínkou je, aby neobsahovala žádné cizorodé složky, pouze 99,9 % Al. Prášek a granule hliníku jsou také vhodné, ale doporučuje se je pro reakci odebírat ve větším množství a výtěžnost nebude tak dobrá jako při použití fólie.

 

[waltjr5858]

I'm not sure 99.9% foil exists. We'll it does and i believe it's labeled 4n and 5n aluminum. Which a roll of that stuff cost at least 2 to 3 hundred possibly more... anything on Amazon or ebay is going to be 98.5 at best like regular renyalds wrap

 

[NieDoswiadczony]

and if I use 99% acetic acid and do not add water, will the reaction be bad?

 

[golab071]

The aluminum amalgam needs some water to function effectively because the reaction Al + H⁺ → H₂ proceeds faster in the presence of water.

In a completely anhydrous environment of IPA + 99% acetic acid, the reaction may slow down or not start at all.
Have you already tried carrying out the reaction? How’s it going?

 

[nofuckups]

how much water exactly? Isn't the leftover water on foil after rinsing sufficient? I use >99% GAA and IPA so I'm wondering if i should add some water to this solution. For a 10g scale, what quanity of water should be added if any? Do we actually need to add water if the foil is wet?

 

[waltjr5858]

Hydrogen actually is bad for the reaction. The reaction takes place on the aluminum surface with the mercury mediating the electron transfer. There's also something else happening to do with protons and a radical something but I forgot the rest. But... hydrogen is coming no matter what obviously.

 

[NieDoswiadczony]

after the reaction of Al with P2np I added NaOH and 2 layers separated but I did not reach pH 12, can I add NaOH solution again to reach pH 12?

 

[GhostChemist]

Yes, you can add an additional portion of NaOH

 

[Johnny Ringo]

Hey guys I want to do this synthesis on big scale in a barrel. In my theory I want to do the amalgam in a seperate bucket with aluminium sheets and then transfer it to the barrel and add the p2np so I can wash the mercury before I start the reaction.
Are there any complications I should look out for or overthink something?


I need at least 3liter oil per synthesis how much p2np would I need for that?

I have some experience with this synthesis and I know what to expect approximately but the result was every time a bit different in terms of yield. For example from 10g I got around 70ml but with pretty high ipa proportion. Then I went up to 25g and I'm pretty sure its because I cooked it with more heat and experimented a bit with the cooling it came out less than with 10g. My theory is its because the ipa evaporated more than usually.
Also I ask myself if its good or bad to dont cool that much like the quality from both runs was solid but when I didnt really cool it the temperature stayed longer stable what should be a good thing right?

Hope somebody here can enlighten me a bit.

 

[waltjr5858]

I would start very small first many times over... this reaction can be finicky and it is beyond easy to lose all precursor... that would suck. A lot of people have had all kinds of issues but once you get good at it I'm sure you could pull it off on a larger scale. Also the aluminum used is fairly important. Regular cheap aluminum foil will most likely result in a failure. Certain alloys are way better suited for this like 1050 or 1100 or if you really want pure stuff 4n or 5n but those are super expensive but very very pure aluminum. I know about the failures intimately and have had tons of them lol.

 

[waltjr5858]

I would start very small first many times over... this reaction can be finicky and it is beyond easy to lose all precursor... that would suck. A lot of people have had all kinds of issues but once you get good at it I'm sure you could pull it off on a larger scale. Also the aluminum used is fairly important. Regular cheap aluminum foil will most likely result in a failure. Certain alloys are way better suited for this like 1050 or 1100 or if you really want pure stuff 4n or 5n but those are super expensive but very very pure aluminum. I know about the failures intimately and have had tons of them lol.

 

[NieDoswiadczony]

hello I have a question about Al/Hg synthesis if when adding sulfuric acid flakes form does it mean everything went well? or if something was wrong in the synthesis will flakes also precipitate

 

[GhostChemist]

it is advisable to always check the product by tests
as for amp

 

[waltjr5858]

That means at least some form of your reaction is an amine so yes that's good but... that doesn't mean that the double bond was also reduced. The only way to verify if the double bond was reduced that is very simple that you can do at home is to react some of your product in its free base form so before you do the salt thing with sulfuric acid take your oil and put a small amount of that in a nonpolar and then add some bromine to a separate beaker containing the same nonpolar and start dripping some of your product in nonpolar into the bromine with nonpolar just small amounts maybe 10 mL of each total with the nonpolar and if the color of the bromine disappears the double bond did not break and you still have an alkene. There are other ways to verify but that one is ridiculously simple.

 

[NieDoswiadczony]

I have a problem with bromine, there is another way to do it at home