Preparation of methamphetamine by phenylalanine method

hacke8

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Prepare reagents: 1-phenylalanine (D/L) optional 2-Sodium carbonate (sodium hydroxide) optional 3-Dimethyl sulfate (methyl iodide) optional 4-Ammonia (for washing reactants) 5-DMF (used to extract reactants) I know the reagents required, but I don’t know the reaction temperature and molar ratio of the reagents. The process is: 1-phenylalanine undergoes decarboxylation under alkaline conditions, 2-Split the flow to obtain amphetamine 3-Amphetamine is then methylated using dimethyl sulfate 4- Wash with ammonia 5-Extraction with DMF This is some information I found on the Internet. I searched some questions on Google. It should be possible to perform this procedure. Chemists with reagents are welcome to operate the process and publish your results.
 
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