reduction

Amphetamine Synthesis from phenylpropanolamine hydrochloride with reduction using I2 and H3PO2. Starting reagents and materials 4.84 g phenylpropanolamine hydrochloride 10.4 g I2 9.4 ml H3PO2 20-50 ml H2O 50 ml 25% NaOH (15-20 г NaOH) 3 g sodium thiosulfate 250-300 ml DCM 30-50 g Na2SO4...

After nabh4 addition is complete and mixed for a few hours after can you let the mix sit for a few hours and the freebase oil layer will rise to the top and can be seperated? this eliminates the need for dcm or toluene extraction but does effect yield.

hey folks, to encourage a more ecological sustainable method for amine reduction than Al/Hg, i want to present you the aluminium-gallium-amalgan method. Basically you can just use al-ga amalgan instead the mercury one and that's it. Actually a ratio of 1:1 between reactant and amalgan, while a...

As per title: I was trying to come up with a stereo-selective synthesis, but I'm stuck at one point where I have to remove a carbonyl. Turning it into an alcohol would vanish the selectivity goal. Now, wherever I look for information it's just people warning about preferring any other way is...