Compared to the reduction of P2NP on aluminum amalgam, this method offers a significantly quieter reaction (The reaction isn't exothermic ), better yield (90%) and a very pure substance (no additional purification required).
Dissolve 15 g of P2N0 in 50 ml of anhydrous acetone
Place 100 ml...
The reactions proceed according to Scheme 1.
Scheme 1.
Starting reagents and materials
5 g purified P2P (P2P obtained through the reduction of P2NP with sodium borohydride and steam distill)
4.1 g Mg
37 г H3CCOONH4 (CAS 631-61-8)
250-300 ml H2O
80 ml EtOH 88%
30 ml HAc
500 ml DCM
5+5 ml Ethyl...
Introduction
Amphetamine and methamphetamine are the most popular synthetic substances and both of them have significant value in modern drug sosiety. They are used at raves, parties, as doping, to get a high and so etc. BB Forum is unique platform in the World, which implements studies of these...
Reactions proceed according to Scheme 1
Reagents and Materials:
8.1 g of aluminum
0.05 g of mercury(II) chloride
5 g P2P
2 g of hydroxylamine or a mixture (50-60 ml of IPA (or ethanol) + 2.5 g of NaOH + 4.55 g of hydroxylamine hydrochloride)
50 ml of ethanol
2-liter flask
2 liters of ice-cold...
Introduction:
A certain vendor online (that shall not be named) appears to be suggesting a "novel" route to phenethylamines.
The reaction from aldehyde to amine occurs in 3 distinct steps:
1) A Baylis-Hillman reaction is first used to couple an aryl aldehyde with acrylamide using a tertiary...
Amphetamine synthesis via NaBH4 reductive amination from P2NP.
https://bbgate.com/threads/one-pot-amphetamine-synthesis-from-p2np-with-nabh4-cucl2-1kg-scale.70/
I found this: One of the most common methods of illegal production of amphetamine is the Leuckart reaction, which consists in the condensation of phenylacetone (phenyl-2-propanone, P2P) with formamide or ammonium formate in the presence of formic acid and subsequent acid hydrolysis of the...
Introduction
At the moment, there are many ways to synthesize dextroamphetamine. They can be divided into 3 types: biosynthesis (using biomass), direct synthesis, and synthesis of racemic (the sum of l- and d-isomers) amphetamine followed by separation of optical isomers. In our case, a...
Reaction scheme:
Equipment and glassware:
50 L batch reactor with a reflux condenser, top stirrer and heating apparatus in a set-up;
Drip funnel;
Conventional funnel;
Laboratory grade thermometer (up to 150 °С);
Several buckets for 10 and 20 L;
Measuring cylinder for 1 L;
Vacuum source...