Propionyl chloride synthesis

[NovicechemistEU]

Propionyl chloride, benzoyl chloride prepared via propionic acid The 1:1 molar ratio of reactants was chosen.


10 mol propionic acid ≈ 747 mL 10 mol benzoyl chloride ≈ 1161 mL (~1:1 molar ratio) in a 2000 mL flask Vertical distillation through a 200 mm column

45-69'C (most collected above 64-69'C) by evacuating a stream of HCl gas from the reaction while finally heating to 190'C to yield 340 g of distillate.
Yield 340 Gr
Note : Really very dangerous synthesis think twice.

 

[NovicechemistEU]

Today I will try another synthesis on a large scale, 5 liters above
1/1 molar ratio 25 mol
Propionic Acid 25 mol **1869 mL
Benzoyl Chloride 25 mol **2903 mL

 

[NovicechemistEU]

I have finished the synthesis but the efficiency is very low, I could not get above 40% maximum, it makes more sense to turn to other ways. Sincerely regards.