Bdo to gbl

Sciencenutz

Don't buy from me
Resident
Joined
Jan 29, 2023
Messages
47
Reaction score
12
Points
8
How do you look up references for synthesis I'm trying to do bdo to gbl and have this but when I look up I can't find the synthesis?

Reaction 5 (Sodium bromite)​

Reagent: sodium bromite
Solvent: H2O acetic acid
Time: 10 hours
Other Conditions: Ambient temperature
Yield 92%
Ref. 1 5666548; Journal; Kageyama, Toshifumi; Kawahara, Shuji; Kitamura, Kohji; Ueno, Yoshio; Okawara, Makoto; CMLTAG; Chem.Lett.; EN; 1983; 1097-1100;
 

UWe9o12jkied91d

Don't buy from me
Resident
Joined
Aug 8, 2022
Messages
675
Reaction score
510
Points
63
Deals
5
But why? 1,4-butanediol is already a prodrug for GHB
Also what else do you need? Everything is here
 

UWe9o12jkied91d

Don't buy from me
Resident
Joined
Aug 8, 2022
Messages
675
Reaction score
510
Points
63
Deals
5
anyways, here you go
https://www.journal.csj.jp/doi/pdf/10.1246/cl.1983.1097
 

Sciencenutz

Don't buy from me
Resident
Joined
Jan 29, 2023
Messages
47
Reaction score
12
Points
8
Where I'm from people are in need of gbl and ghb as bdo isn't acceptable. I have been having issues with bdo to gbl with copper chromite as for some reason on my heating mantle I can't get the temp to 200c...it stops at around 190c and then slowly drops...even though my mantle temp can easily get it to over 200c it just doesn't seem to want to go higher
 

UWe9o12jkied91d

Don't buy from me
Resident
Joined
Aug 8, 2022
Messages
675
Reaction score
510
Points
63
Deals
5
They smell very simillar, the smell is weak so not even as discernable, with very simillar effects for GBL atleast.
 

Sciencenutz

Don't buy from me
Resident
Joined
Jan 29, 2023
Messages
47
Reaction score
12
Points
8
Also how did you search that ref # I have a few others I'm interested in
 

UWe9o12jkied91d

Don't buy from me
Resident
Joined
Aug 8, 2022
Messages
675
Reaction score
510
Points
63
Deals
5
I’ll try to find the rest if you provide them, reaserch is what I do for a living, don’t feel like writing a guide rn
 

Sciencenutz

Don't buy from me
Resident
Joined
Jan 29, 2023
Messages
47
Reaction score
12
Points
8
Reagent: NaBrO2*3H20, Al2O3
Solvent: CH2Cl2
Other Conditions: Ambient temperature
Yield 92%
Ref. 1 5895926; Journal; Morimoto, Takashi; Hirano, Masao; Iwasaki, Keiko; Ishikawa, Takashi; CMLTAG; Chem.Lett.; EN; 1; 1994; 53-54;
 

Sciencenutz

Don't buy from me
Resident
Joined
Jan 29, 2023
Messages
47
Reaction score
12
Points
8
Have you done bdo to gbl with copper chromite at 200c before? I'm having trouble converting it I can only get to 190c and temp drops around 13c and hydrogen occurs boil for 3 4 hours then distill but when put in freezer it goes solid any ideas?
 

Alkahest

Don't buy from me
Member
Joined
Oct 23, 2023
Messages
2
Reaction score
3
Points
3
Reflux longer. Check periodically the evolution of hydrogen by attaching a balloon or something to the reflux condenser. Ignite it to verify. You will know that it has gone to completion when the reaction mixture is cooled and it has the consistency close to that of water. Also, consider using other copper catalysts, copper chromite is toxic, particularly devastating to aquatic life, don't pour down the sink. You should spend time to properly purify the end product.
 
Top