Hello friends, have you tried the method of making DMT with sodium formaldehyde bisulfite and triethyl amine?
In this clip, Hamilton synthesizes
In this clip, Hamilton synthesizes
Making DMT with sodium formaldehyde bisulfite and triethyl amine???
- Thread starter Joker_55555
- Start date
8g of NaBH4 was suspended in cold DCM, 40ml of glacial acetic acid was added dropwise and the solution was let to stir until all hydrogen evolution has stopped.
In another rbf, 10g of 5-methoxytryptamine was dissolved in DCM. 8ml of triethylamine, 21.2g of formaldehyde bisulfite adduct and 4A sieves was added to the rbf.
The rbf was left to stir for 10-15 minutes to let the reactants condense and then the sodium triacetoxyborohydride which was made previously was added dropwise.
This was let to stir for roughly 24 hours. The reaction was quenched with dropwise addition of 15% KOH solution and a simple amine workup was done to retrieve the product which crystallised with no issues. Using sodium triacetoxyborohydride I always yield 90%+
In another rbf, 10g of 5-methoxytryptamine was dissolved in DCM. 8ml of triethylamine, 21.2g of formaldehyde bisulfite adduct and 4A sieves was added to the rbf.
The rbf was left to stir for 10-15 minutes to let the reactants condense and then the sodium triacetoxyborohydride which was made previously was added dropwise.
This was let to stir for roughly 24 hours. The reaction was quenched with dropwise addition of 15% KOH solution and a simple amine workup was done to retrieve the product which crystallised with no issues. Using sodium triacetoxyborohydride I always yield 90%+
↑View previous replies…
You aware that this yields 5-MeO-DMT, not DMT right?
I doubt you actually tried the procedure yourself like you claim to have done. There is NO FUCKING WAY you accidentally made 5-MeO-DMT instead and did not notice.
Cmon man. For DMT you need tryptamine. For 5-MeO-DMT you use 5-Methoxytryptamine specifically due the the methoxy group in 5-MeO-DMT...
I doubt you actually tried the procedure yourself like you claim to have done. There is NO FUCKING WAY you accidentally made 5-MeO-DMT instead and did not notice.
Cmon man. For DMT you need tryptamine. For 5-MeO-DMT you use 5-Methoxytryptamine specifically due the the methoxy group in 5-MeO-DMT...
- By huanf
Bro ,take easy， you have absolutely no idea what I mean when I ask you, that means “this method works with 5-Methoxytryptamine instead of tryptamine, right?" same way Hamilton said in the video that he was using tryptamine, but I saw that the solution was not the trytamine color, and I tried this procedure and it didn't work, and you mentioned the same procedure with 5-Methoxytryptamine." now we clear？ should i prove you ？！！Don't be suspicious when you don't know nothing
Attachments
Do you make 5-meo -dmt with this method ?? In the clip, Hamilton uses dichloroethane and the fact that you are using methylene chloride does not react with methylene chloride ?? He also uses the microwave
Can you explain the extraction method more? For more details (Hamilton takes the DMT using the crystal fumarate method) thank you
Can you explain the extraction method more? For more details (Hamilton takes the DMT using the crystal fumarate method) thank you
I also want to synthesize sodium formaldehyde bisulfite but I can not find a way to synthesize it. You have a way to synthesize this substance؟
Thank you.
Thank you.
Dichloroethane is superior solvent for this. I just didn't have it on hand.
The reaction happens only with the end product (Tertiary amines are way more prone to attack by DCM) and at low amounts.
After quenching the reaction with 15% KOH, transfer all of it to a separatory funnel, separate the organic, wash with dilute KOH, saturated NaCl, dry with MgSO4. Distill the DCM off, extract with boiling heptane and put in freezer
The reaction happens only with the end product (Tertiary amines are way more prone to attack by DCM) and at low amounts.
After quenching the reaction with 15% KOH, transfer all of it to a separatory funnel, separate the organic, wash with dilute KOH, saturated NaCl, dry with MgSO4. Distill the DCM off, extract with boiling heptane and put in freezer
And 5-meo-dmt is synthesized?
I thought this method did not work on maxamine and was only for tryptamine.
Is the purity of 5-meo-dmt good?
And can mexamine chloride be used? thank you
I thought this method did not work on maxamine and was only for tryptamine.
Is the purity of 5-meo-dmt good?
And can mexamine chloride be used? thank you
.
And 5-meo-dmt is synthesized?
I thought this method did not work on maxamine and was only for tryptamine.
Is the purity of 5-meo-dmt good?
And can mexamine chloride be used? thank you
And 5-meo-dmt is synthesized?
I thought this method did not work on maxamine and was only for tryptamine.
Is the purity of 5-meo-dmt good?
And can mexamine chloride be used? thank you
I also want to synthesize sodium formaldehyde bisulfite but I can not find a way to synthesize it. You have a way to synthesize this substance؟
Thank you.
Thank you.
100g of paraformaldehyde and small amount of KOH was added to 200ml of water at 70C. This was let to stir for an hour and then gradually added to a rbf with 100ml of water and 150g of sodium sulfite.
This took abit over a hour and once done was let to stir for 15 minutes. The solution was concentrated and cooled to 0C with an ice bath. 80ml of EtOH was added and the rbf was shaken to kick start crystalisation.
The crystals were filted out and washed twice with the filtrate. The crystals were dried over a few hours in an oven.
This took abit over a hour and once done was let to stir for 15 minutes. The solution was concentrated and cooled to 0C with an ice bath. 80ml of EtOH was added and the rbf was shaken to kick start crystalisation.
The crystals were filted out and washed twice with the filtrate. The crystals were dried over a few hours in an oven.
Thank you. Only with formaldehyde 37% How to do this I think in the first step you convert paraformaldehyde to formaldehyde.
- By Tryptamine
Did you make Formaldehyde bisulfite adduct with 37% formaldehyde? how did it went?
↑View previous replies…
- By Joker_55555
I added sodium bisulfite to 37% formaldehyde and dried it with heat. The melting point is around 190 degrees.
- By Tryptamine
How much sodium bisulfite you used? if I want to make Formaldehyde bisulfite adduct out of 100ml 37% formaldehyde solution how much do I need?
- By Joker_55555
You can go ahead with the molar ratio, but I poured 5 ml for one gram and then let it evaporate on the heater.
You can test this test and get the melting point and report to me
You can test this test and get the melting point and report to me
- By Tryptamine
Does sodium bisulfite reacts with formaldehyde and leave no sodium bisulfite? I'm kinda worried about sodium bisulfite residue
- By Joker_55555
When I tried to get the melting point of the substance, about half of the substance melts at 190 degrees, not half of it, maybe some part didn't react, I don't know why
- By Tryptamine
I got one product from sigma-aldrich it was bit expensive I use chemical from chemical supplier.
~30ml
- By Joker_55555
Hello, I did the reaction, finally the solvent was removed at room temperature, but I poured the yellow oil into hot heptane, why didn't it dissolve?